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lactis atcc 19435 t (ATCC)

Name: lactis atcc 19435 t
Brand: ATCC
Rating: 95 (244 reviews)

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ATCC lactis atcc 19435 t
Lactis Atcc 19435 T, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 244 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 95 stars, based on 244 article reviews

lactis atcc 19435 t - by Bioz Stars, 2026-02

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a, Principal coordinate analysis plot of amplicon sequence variant abundances in fecal samples from rats after 30-day consumption of the AGE-rich diet (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity, coordinates 3 and 4; R =0.09, P=0.046). b , Fecal Lactococcus abundance (n=12 CTL, n=12 AGE-rich; non-parametric Wilcoxon rank sum test; P=1.48×10 - , FDR=1.58×10 - ). c , Correlation between NOIC performance (percent shift from baseline) and Lactococcus abundance (Spearman’s correlation, rho=0.743, P=7.56×10 - , FDR=0.0121). d , Lactococcus lactis subspecies lactis abundance in diet samples (n=3 CTL diet, n=3 AGE-rich diet; unpaired two-tailed t-test, P=0.0006). e , Experimental timeline for Lactococcus supplementation experiments. f , Lactococcus lactis subspecies lactis abundance in stomach content 2 h post-meal (n=8 AGE-rich - SAL, n=8 AGE-rich - LAC; unpaired two-tailed t-test, P<0.0001). g , Total object exploration time during NOIC day 1 (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; unpaired two-tailed t-test, P=0.28). h , NOIC percent shift from baseline object exploration (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; Welch’s t-test, P=0.02; one-sample t-test for difference from 0 [chance], P=0.77 AGE-rich - SAL, P=0.0003 AGE-rich - LAC). i , Total object exploration time during the initial exposure period for NOR (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; unpaired two-tailed t-test, P=0.16). j , NOR object exploration index during the test exposure period (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; unpaired two-tailed t-test, P=0.52; one-sample t-test for difference from 0.5 [chance], P=0.0004 AGE-rich - SAL, P=0.004 AGE-rich - LAC). Error bars represent standard error of the mean (SEM).*P<0.05, ***P<0.001, ****P<0.0001. # indicates statistically significant difference from chance (P<0.05), which was 0.0 for NOIC and 0.5 for NOR. All n’s indicate number of rats or samples per group. Additional details about the statistical analyses for each subpanel can be found in . AGE, advanced glycation end-product; ANOVA, analysis of variance; ASV, amplicon sequence variant; CFU, colony forming unit; CTL, control [diet]; FDR, false discovery rate; LAC, Lactococcus ; NOIC, novel object in context; NOR, novel object recognition; PN, postnatal day; SAL, saline [vehicle].

Journal: bioRxiv

Article Title: Consumption of processed foods impairs memory function through dietary advanced glycation end-products

doi: 10.64898/2026.01.07.698065

Figure Lengend Snippet: a, Principal coordinate analysis plot of amplicon sequence variant abundances in fecal samples from rats after 30-day consumption of the AGE-rich diet (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity, coordinates 3 and 4; R =0.09, P=0.046). b , Fecal Lactococcus abundance (n=12 CTL, n=12 AGE-rich; non-parametric Wilcoxon rank sum test; P=1.48×10 - , FDR=1.58×10 - ). c , Correlation between NOIC performance (percent shift from baseline) and Lactococcus abundance (Spearman’s correlation, rho=0.743, P=7.56×10 - , FDR=0.0121). d , Lactococcus lactis subspecies lactis abundance in diet samples (n=3 CTL diet, n=3 AGE-rich diet; unpaired two-tailed t-test, P=0.0006). e , Experimental timeline for Lactococcus supplementation experiments. f , Lactococcus lactis subspecies lactis abundance in stomach content 2 h post-meal (n=8 AGE-rich - SAL, n=8 AGE-rich - LAC; unpaired two-tailed t-test, P<0.0001). g , Total object exploration time during NOIC day 1 (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; unpaired two-tailed t-test, P=0.28). h , NOIC percent shift from baseline object exploration (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; Welch’s t-test, P=0.02; one-sample t-test for difference from 0 [chance], P=0.77 AGE-rich - SAL, P=0.0003 AGE-rich - LAC). i , Total object exploration time during the initial exposure period for NOR (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; unpaired two-tailed t-test, P=0.16). j , NOR object exploration index during the test exposure period (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; unpaired two-tailed t-test, P=0.52; one-sample t-test for difference from 0.5 [chance], P=0.0004 AGE-rich - SAL, P=0.004 AGE-rich - LAC). Error bars represent standard error of the mean (SEM).*P<0.05, ***P<0.001, ****P<0.0001. # indicates statistically significant difference from chance (P<0.05), which was 0.0 for NOIC and 0.5 for NOR. All n’s indicate number of rats or samples per group. Additional details about the statistical analyses for each subpanel can be found in . AGE, advanced glycation end-product; ANOVA, analysis of variance; ASV, amplicon sequence variant; CFU, colony forming unit; CTL, control [diet]; FDR, false discovery rate; LAC, Lactococcus ; NOIC, novel object in context; NOR, novel object recognition; PN, postnatal day; SAL, saline [vehicle].

Article Snippet: Lactococcus lactis subspecies lactis strain NCTC 6681 (Lister, Schleifer et al., cat. no. 19435) was purchased from the American Type Culture Collection (ATCC, Manassas, VA, USA), rehydrated, and inoculated according to manufacturer’s instructions.

Techniques: Amplification, Sequencing, Variant Assay, Two Tailed Test, Control, Saline

a , Microbiome principal coordinate analysis (PCoA) plot for the genus level from fecal samples collected at PN 56 in rats that consumed a heat-treated AGE-rich diet vs. non-heat-treated diet during early life (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity; R =0.08746, P=0.062). b , Microbiome PCoA plot for the genus level from fecal samples collected at PN 90 in rats that consumed a heat-treated AGE-rich diet vs. non-heat-treated diet during early life (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity; R =0.06386, P=0.149). c , Microbiome PCoA plot for the genus level from fecal samples collected at PN 102 in rats that consumed a heat-treated AGE-rich diet vs. non-heat-treated diet during early life (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity; R =0.09077, P=0.046). d , Microbiome PCoA plot for the ASV level from fecal samples collected at PN 56 in rats that consumed a heat-treated AGE-rich diet vs. non-heat-treated diet during early life (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity; R =0.08746, P=0.062). e , Microbiome PCoA plot for the ASV level from fecal samples collected at PN 90 in rats that consumed a heat-treated AGE-rich diet vs. non-heat-treated diet during early life (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity; R =0.0769, P=0.014). f , Microbiome PCoA plot for the ASV level from fecal samples collected at PN 102 in rats that consumed a heat-treated AGE-rich diet vs. non-heat-treated diet during early life (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity; R =0.05991, P=0.072). g , Streptococcaceae (family) abundance in fecal samples at PN 56 (n=12 CTL, n=12 AGE-rich; Non-parametric Wilcoxon rank sum test; P=1.48×10 - , FDR=1.58×10 - ). h , Lactococcus (genus) abundance in fecal samples at PN 56 (n=12 CTL, n=12 AGE-rich; Non-parametric Wilcoxon rank sum test; P=1.48×10 - , FDR=1.58×10 - ). i , Defluviitaleaceae_UCG-011 (genus) abundance in fecal samples at PN 56 (n=12 CTL, n=12 AGE-rich; Non-parametric Wilcoxon rank sum test; P=0.0013, FDR=0.044). j , Uncultured organism (species) abundance in fecal samples at PN 56 (n=12 CTL, n=12 AGE-rich; Non-parametric Wilcoxon rank sum test; P=0.0013, FDR=0.044). k , Roseburia (genus) abundance in fecal samples at PN 56 (n=12 CTL, n=12 AGE-rich; Non-parametric Wilcoxon rank sum test; P=0.0016, FDR=0.053). l , Anaerovoracaceae (family) abundance in fecal samples at PN 56 (n=12 CTL, n=12 AGE-rich; Non-parametric Wilcoxon rank sum test; P=8.63×10 - , FDR=0.044). m , Correlation between NOIC performance and Lactococcus (genus) abundance (n=12 CTL, n=12 AGE-rich; Spearman’s correlation; rho=0.743, P=7.56×10 - , FDR=0.0121). n , Correlation between NOIC performance and UCG-005 (genus) uncultured Clostridiales (species) abundance (n=12 CTL, n=12 AGE-rich; Spearman’s correlation; rho=0.62, P=0.00159, FDR=0.0593). o , Correlation between NOIC performance and Anaerovoracaceae (family) abundance (n=12 CTL, n=12 AGE-rich; Spearman’s correlation; rho=-0.618, P=0.00169, FDR=0.0593). p , Correlation between NOIC performance and UCG-005 (genus) abundance (n=12 CTL, n=12 AGE-rich; Spearman’s correlation; rho=-0.613, P=0.00185, FDR=0.0593). q , Shannon index for genus level abundances at PN 56 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.41). r , Shannon index for genus level abundances at PN 90 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.88). s , Shannon index for genus level abundances at PN 102 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.98). t , Shannon index for species level abundances at PN 56 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.38). u , Shannon index for species level abundances at PN 90 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.74). v , Shannon index for species level abundances at PN 102 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.83). w , Shannon index for ASV level abundances at PN 56 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.49). x , Shannon index for ASV level abundances at PN 90 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.35). y , Shannon index for ASV level abundances at PN 102 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.49). Error bars represent standard error of the mean (SEM).*P<0.05, ***P<0.001, ****P<0.0001. All n’s indicate number of rats or samples per group. Additional details about the statistical analyses for each subpanel can be found in . AGE, advanced glycation end-product; ASV, amplicon sequence variant; CTL, control [diet]; FDR, false discovery rate; PN, postnatal day; PCoA, principal coordinate analysis.

Journal: bioRxiv

Article Title: Consumption of processed foods impairs memory function through dietary advanced glycation end-products

doi: 10.64898/2026.01.07.698065

Figure Lengend Snippet: a , Microbiome principal coordinate analysis (PCoA) plot for the genus level from fecal samples collected at PN 56 in rats that consumed a heat-treated AGE-rich diet vs. non-heat-treated diet during early life (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity; R =0.08746, P=0.062). b , Microbiome PCoA plot for the genus level from fecal samples collected at PN 90 in rats that consumed a heat-treated AGE-rich diet vs. non-heat-treated diet during early life (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity; R =0.06386, P=0.149). c , Microbiome PCoA plot for the genus level from fecal samples collected at PN 102 in rats that consumed a heat-treated AGE-rich diet vs. non-heat-treated diet during early life (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity; R =0.09077, P=0.046). d , Microbiome PCoA plot for the ASV level from fecal samples collected at PN 56 in rats that consumed a heat-treated AGE-rich diet vs. non-heat-treated diet during early life (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity; R =0.08746, P=0.062). e , Microbiome PCoA plot for the ASV level from fecal samples collected at PN 90 in rats that consumed a heat-treated AGE-rich diet vs. non-heat-treated diet during early life (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity; R =0.0769, P=0.014). f , Microbiome PCoA plot for the ASV level from fecal samples collected at PN 102 in rats that consumed a heat-treated AGE-rich diet vs. non-heat-treated diet during early life (n=12 CTL, n=12 AGE-rich; Bray-Curtis dissimilarity; R =0.05991, P=0.072). g , Streptococcaceae (family) abundance in fecal samples at PN 56 (n=12 CTL, n=12 AGE-rich; Non-parametric Wilcoxon rank sum test; P=1.48×10 - , FDR=1.58×10 - ). h , Lactococcus (genus) abundance in fecal samples at PN 56 (n=12 CTL, n=12 AGE-rich; Non-parametric Wilcoxon rank sum test; P=1.48×10 - , FDR=1.58×10 - ). i , Defluviitaleaceae_UCG-011 (genus) abundance in fecal samples at PN 56 (n=12 CTL, n=12 AGE-rich; Non-parametric Wilcoxon rank sum test; P=0.0013, FDR=0.044). j , Uncultured organism (species) abundance in fecal samples at PN 56 (n=12 CTL, n=12 AGE-rich; Non-parametric Wilcoxon rank sum test; P=0.0013, FDR=0.044). k , Roseburia (genus) abundance in fecal samples at PN 56 (n=12 CTL, n=12 AGE-rich; Non-parametric Wilcoxon rank sum test; P=0.0016, FDR=0.053). l , Anaerovoracaceae (family) abundance in fecal samples at PN 56 (n=12 CTL, n=12 AGE-rich; Non-parametric Wilcoxon rank sum test; P=8.63×10 - , FDR=0.044). m , Correlation between NOIC performance and Lactococcus (genus) abundance (n=12 CTL, n=12 AGE-rich; Spearman’s correlation; rho=0.743, P=7.56×10 - , FDR=0.0121). n , Correlation between NOIC performance and UCG-005 (genus) uncultured Clostridiales (species) abundance (n=12 CTL, n=12 AGE-rich; Spearman’s correlation; rho=0.62, P=0.00159, FDR=0.0593). o , Correlation between NOIC performance and Anaerovoracaceae (family) abundance (n=12 CTL, n=12 AGE-rich; Spearman’s correlation; rho=-0.618, P=0.00169, FDR=0.0593). p , Correlation between NOIC performance and UCG-005 (genus) abundance (n=12 CTL, n=12 AGE-rich; Spearman’s correlation; rho=-0.613, P=0.00185, FDR=0.0593). q , Shannon index for genus level abundances at PN 56 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.41). r , Shannon index for genus level abundances at PN 90 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.88). s , Shannon index for genus level abundances at PN 102 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.98). t , Shannon index for species level abundances at PN 56 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.38). u , Shannon index for species level abundances at PN 90 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.74). v , Shannon index for species level abundances at PN 102 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.83). w , Shannon index for ASV level abundances at PN 56 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.49). x , Shannon index for ASV level abundances at PN 90 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.35). y , Shannon index for ASV level abundances at PN 102 (n=12 CTL, n=12 AGE-rich; Shannon index (alpha-diversity); P=0.49). Error bars represent standard error of the mean (SEM).*P<0.05, ***P<0.001, ****P<0.0001. All n’s indicate number of rats or samples per group. Additional details about the statistical analyses for each subpanel can be found in . AGE, advanced glycation end-product; ASV, amplicon sequence variant; CTL, control [diet]; FDR, false discovery rate; PN, postnatal day; PCoA, principal coordinate analysis.

Techniques: Amplification, Sequencing, Variant Assay, Control

a , Change in body weight over time in rats receiving the AGE-rich diet with or without Lactococcus supplementation (PN 26-41) from PN 26-60 followed by standard chow (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; 2-way ANOVA, supplement group [P=0.8345], time [P<0.0001], supplement group × time [P=0.0277]; no post-hoc comparisons were statistically significant). b , Lactococcus lactis subspecies lactis colony counts across supplementation days (count performed on 3 samples, no statistical analyses performed). c , Lactococcus lactis subspecies lactis abundance in cecal content (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; Welch’s t-test, P=0.2709). d , Total object exploration time during NOIC day 3 (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; unpaired two-tailed t-test, P=0.1477). e , Discrimination index during NOIC day 1 (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; unpaired two-tailed t-test, P=0.1198). f , Total object exploration time during the final exposure period of NOR (n=7 AGE-rich - SAL, n=6 AGE-rich - LAC; unpaired two-tailed t-test, P=0.4052). g , Percent time in the open arm zones during the zero maze test (n=7 AGE-rich - SAL, n=6 AGE-rich - LAC; Welch’s t-test, P=0.2131). h , Entries into the open arm zones during the zero maze test (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; Welch’s t-test, P=0.2303). i , Time spent in the center zone during the open field test (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; Welch’s t-test, P=0.0815). j , Distance travelled during the open field test (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; Welch’s t-test, P=0.0504). Error bars represent standard error of the mean (SEM). All n’s indicate number of rats per group. Additional details about the statistical analyses for each subpanel can be found in . AGE, advanced glycation end-product; CTL, control [diet]; LAC, Lactococcus ; NOIC, novel object in context; NOR, novel object recognition; PN, postnatal day; SAL, saline [vehicle].

Journal: bioRxiv

Article Title: Consumption of processed foods impairs memory function through dietary advanced glycation end-products

doi: 10.64898/2026.01.07.698065

Figure Lengend Snippet: a , Change in body weight over time in rats receiving the AGE-rich diet with or without Lactococcus supplementation (PN 26-41) from PN 26-60 followed by standard chow (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; 2-way ANOVA, supplement group [P=0.8345], time [P<0.0001], supplement group × time [P=0.0277]; no post-hoc comparisons were statistically significant). b , Lactococcus lactis subspecies lactis colony counts across supplementation days (count performed on 3 samples, no statistical analyses performed). c , Lactococcus lactis subspecies lactis abundance in cecal content (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; Welch’s t-test, P=0.2709). d , Total object exploration time during NOIC day 3 (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; unpaired two-tailed t-test, P=0.1477). e , Discrimination index during NOIC day 1 (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; unpaired two-tailed t-test, P=0.1198). f , Total object exploration time during the final exposure period of NOR (n=7 AGE-rich - SAL, n=6 AGE-rich - LAC; unpaired two-tailed t-test, P=0.4052). g , Percent time in the open arm zones during the zero maze test (n=7 AGE-rich - SAL, n=6 AGE-rich - LAC; Welch’s t-test, P=0.2131). h , Entries into the open arm zones during the zero maze test (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; Welch’s t-test, P=0.2303). i , Time spent in the center zone during the open field test (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; Welch’s t-test, P=0.0815). j , Distance travelled during the open field test (n=8 AGE-rich - SAL, n=6 AGE-rich - LAC; Welch’s t-test, P=0.0504). Error bars represent standard error of the mean (SEM). All n’s indicate number of rats per group. Additional details about the statistical analyses for each subpanel can be found in . AGE, advanced glycation end-product; CTL, control [diet]; LAC, Lactococcus ; NOIC, novel object in context; NOR, novel object recognition; PN, postnatal day; SAL, saline [vehicle].

Techniques: Two Tailed Test, Control, Saline